|
|
||||||
|
Biomedical and Radiation-Genetic Studies Using Different Types of Ionizing Radiation
| Leader: | G.V. Mitsyn |
| Deputy: | S.V. Shvidky |
Participating countries and international organizations:
Czech Republic, India, Poland, Romania, Russia.
Issues addressed and main goals of research:
Medico-biological and clinical research for the proton radiotherapy of cancer patients. Formatian of experimental data base in the field of radiation mutagenesis in the animal germ cells.
Expected major results in the current year:
- Continuation of clinical researches on proton therapy of cancer patients in Room 1. Evaluation of the effectiveness of the conducted radiation treatment of different neoplasms.
- Work to increase the functional capability of the developed 3D treatment planning software and its clinical tests in the treatment sessions.
- Test of the prototype equipment for the dynamic conformal irradiation of deep-seated tumours with the proton beam.
- Development and improvement of detectors and tools for the clinical dosimetry of the medical hadron beams.
- Exploration of the possibilities of laser radioprotection against damage after exposure to ionizing radiation on mouse fibroblast cells with the application of laser module with a wave length of 532 nm.
- Investigations of the molecular spectra of gene mutations induced by different quality ionizing radiation in animal germ cells.
| List of projects: | |||
| Project | Leader | Priority (period of realisation) |
|
| 1. | Further development of methods, technologies, schedule modes and delivery of radiotherapy |
G.V. Mitsyn K.Sh. Voskanyan |
1 (2017-2019) |
| 2. | RADIOGENE: Experimental justification of radiation genetic risk estimation according to the frequency of heritable DNA changes in human and animal structural genes |
I.D. Alexandrov | 1 (2017-2019) |
| List of Activities | |||||
| Activity or Experiment | Leaders | ||||
| Laboratory or other Division of JINR Responsible person |
Main researchers | ||||
| 1. | Further development of methods, technologies, schedule modes and delivery of radiotherapy |
G.V. Mitsyn K.Sh. Voskanyan |
|
||
| DLNP | A.V. Agapov, I.V. Alexandrova, K. Belokopytova, V.M. Breyev, D.M. Borovich, T.L. Demakova, G.V. Donskaya, V.N. Gaevsky, A.E. Ivanova, Ye.I. Luchin, I.I. Klochkov, I.Ye. Miller, A.G. Molokanov, K. Oancea, S.A. Pisareva, A.V. Rzyanina, K.N. Shipulin, M.A. Tseytlina | ||||
| 2. | RADIOGENE: Experimental justification of radiation-genetic risk estimation according to the frequency of heritable DNA changes in human and animal structural genes |
I.D. Alexandrov |
|
||
| DLNP | M.V. Alexandrova, K.P. Afanasyeva, S.V. Dubovik, N.E. Kharchenko, S.V. Korablinova, L.N. Korovina, Ye.V. Kravchenko, N.E. Kharchenko, E.S. Mayarova, N.V. Orlova, A.N. Rusakovich | ||||
| Collaboration | |||
| Country or International Organization |
City | Institute or Laboratory | |
| Czech Republic | Rez | UJV | |
| Prague | PTC | ||
| India | Mumbai | BARC | |
| New Delhi | IUAC | ||
| Moldova | Chisinau | MSU | |
| Poland | Krakow | NINP PAS | |
| Otwock-Swierk | NCBJ | ||
| Poznan | GPCC | ||
| Romania | Bucharest | UMF | |
| UB | |||
| Russia | Moscow | VIGG RAS | |
| IBMP RAS | |||
| RMAPE | |||
| Dubna | RDH-9 | ||
| Rostov-on-Don | SFedU |