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and Photoluminescence for Condensed Matter Studies
| Leaders: | G.M. Arzumanyan N. Kučerka |
Participating countries and international organizations:
Armenia, Belarus, Bulgaria, Cuba, Egypt, Poland, Romania, Russia, Slovakia, Ukraine, Uzbekistan.
Issues addressed and main goals of research:
Fundamental and applied research in the field of spontaneous and nonlinear Raman microspectroscopy aimed at highly sensitive biosensing. Study of mechanisms and nature of surface-enhanced Raman scattering (SERS) taking into account the anomalous ratio of line intensities in the anti-Stokes and Stokes spectral regions. Development of ultralow-frequency Raman spectroscopy for biomedical purposes, including early diagnostics.
Expected results in the current year:
- Development of a technique for simultaneous registration of Stokes and anti-Stokes components in SERS spectra.
- Revealing a possible nonlinear dependence of SERS spectra on the pump power.
- Detailed characterization of Raman spectra of liposomes with embedded proteins.
- Search and identification of the Raman marker of NETosis for the purposes of early diagnostics.
- Acquisition and registration of spectra using optics adapted for low-frequency Raman spectroscopy.
| List of projects: | |||
| Project | Leaders | Priority (period of realisation) |
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| 1. | BIOPHOTONICS | G.M. Arzumanyan N. Kučerka Deputy: K.Z. Mamatkulov |
1 (2021-2023) |
| List of Activities | |||||
| Activity or Experiment | Leaders | ||||
| Laboratory or other Division of JINR |
Main researchers | ||||
| 1. | Study of the features of Stokes and anti-Stokes components of SERS spectra from analyte molecules in order to understand the processes of enhancement in SERS spectroscopy | G.M. Arzumanyan |
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| FLNP | K.Z. Mamatkulov, I.A. Morkovnikov + 2 engineers | ||||
| 2. | Determination of the range of pump intensities for recording reproducible aSt / St spectra | G.M. Arzumanyan K.Z. Mamatkulov |
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| FLNP | M.Yu. Vorobyeva, S.P. Marmakov + 1 engineer | ||||
| 3. | Stabilization of membrane proteins and studies of their structure using lipodiscs/liposomes by Raman spectroscopy, electron microscopy and SANS | G.M. Arzumanyan N. Kučerka |
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| FLNP | K.Z. Mamatkulov, M.Yu. Vorobyeva, A. Damir | ||||
| 4. | Testing the technique for obtaining Raman spectra of lipodiscs/liposomes with membrane proteins and “empty” lipodiscs/liposomes | K.Z. Mamatkulov N. Kučerka |
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| FLNP | M.Yu. Vorobyeva, A. Damir + 2 engineers | ||||
| 5. | Study of the influence of lipid environment on the structure of membrane protein | G.M. Arzumanyan N. Kučerka |
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| FLNP | K.Z. Mamatkulov, M.Yu. Vorobyeva, K.Sh. Voskanyan + 1 engineer + 2 laboratory assistant | ||||
| 6. | Search for spectral / Raman markers of NETosis | G.M. Arzumanyan N. Kučerka |
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| FLNP | K.Z. Mamatkulov, M.Yu. Vorobyeva, + 1 engineer + 2 laboratory assistant | ||||
| 7. | Study of mechanisms of sterile activation of NETosis under UV radiation | G.M. Arzumanyan K.Z. Mamatkulov |
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| FLNP | M.Yu. Vorobyeva, K.Sh. Voskanyan, A. Damir | ||||
| 8. | Mastering the technique of ultra-low frequency Raman spectroscopy ~ (5-10) cm-1. | G.M. Arzumanyan K.Z. Mamatkulov |
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| FLNP | M.Yu. Vorobyeva, S.P. Marmakov + 2 engineers | ||||
Collaboration
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Country or International Organization |
City | Institute or laboratory |
| Armenia | Yerevan | Foundation ANSL |
| Belarus | Minsk | BSUIR |
| SOL instruments | ||
| Bulgaria | Sofia | ISSP BAS |
| Cuba | Havana | InSTEC |
| Egypt | Giza | CU |
| Poland | Krakow | JU |
| Romania | Cluj-Napoca | INCDTIM |
| Magurele | NIMP | |
| Russia | Moscow | GPI RAS |
| LMPR MONIKI | ||
| MSU | ||
| Slovakia | Kosice | UPJS |
| Ukraine | Donetsk | DonNU |
| Uzbekistan | Jizzakh | JSPI |
